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RESEARCH

Medical Literature

Intra-articular injection of mesenchymal stem cells for the treatment of osteoarthritis of the knee: a proof-of-concept clinical trial. Jo CH, Lee YG, Shin WH, Kim H, Chai JW, Jeong EC, Kim JE, Shim H, Shin JS, Shin IS, Ra JC, Oh S, Yoon KS. Stem Cells. 2014 May;32(5):1254-66. doi: 10.1002/stem.1634.

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Paracrine effect of mesenchymal stem cells derived from human adipose tissue in bone regeneration. Linero I, Chaparro O. PLoS One. 2014 Sep 8;9(9):e107001. doi: 10.1371/journal.pone.0107001. eCollection 2014.

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20 Research Articles On: Preclinical and clinical data for the use of mesenchymal stem cells in articular cartilage tissue engineering. Tang QO, Carasco CF, Gamie Z, Korres N, Mantalaris A, Tsiridis E. Expert Opin Biol Ther. 2012 Oct;12(10):1361-82. Epub 2012 Jul 12.

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Treatment of knee osteoarthritis with autologous mesenchymal stem cells: a pilot study. Orozco L1, Munar A, Soler R, Alberca M, Soler F, Huguet M, Sentís J, Sánchez A, García-Sancho J. Transplantation. 2013 Jun 27;95(12):1535-41

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Autologous bone marrow concentrate: review and application of a novel intra-articular orthobiologic for cartilage disease. Sampson S1, Botto-van Bemden A, Aufiero D. Phys Sportsmed. 2013 Sep;41(3):7-18.

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Clinical outcome of autologous bone marrow aspirates concentrate (BMAC) injection in degenerative arthritis of the knee. Jae-Do Kim, Gun Woo Lee, Gu Hee Jung, Cheung Kue Kim, Taehun Kim, Jin Hyung Park, Seong Sook Cha, Young-Bin You, European Journal of Orthopaedic Surgery & Traumatology, January 2014

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Regenerative injection therapy with whole bone marrow aspirate for degenerative joint disease: a case series. Hauser RA1, Orlofsky A. Clin Med Insights Arthritis Musculoskelet Disord. 2013 Sep 4;6:65-72.

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Treatment of chronic patellar tendinopathy with autologous bone marrow stem cells: a 5-year-followup. Pascual-Garrido C, et al. Stem Cells Int. 2012; Epub 2011 Dec 18.

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Safety of autologous bone marrow aspiration concentrate transplantation: initial experiences in 101 patients. Hendrich C1, Franz E, Waertel G, Krebs R, Jäger M. Orthop Rev (Pavia). 2009 Oct 10;1(2):e32

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Treatment of a hip capsular injury in a professional soccer player with platelet-rich plasma and bone marrow aspirate concentrate therapy. Kevin J. Campbell • Robert E. Boykin, Coen A. Wijdicks • J. Erik Giphart • Robert F. LaPrade • Marc J. Philippon, Knee Surg Sports Traumatol Arthrosc - Received: 9 August 2012 / Accepted: 24 September 2012

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Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: a case series. Pak J . J Med Case Rep 2011, 5:296.

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Stem cells and cartilage development: complexities of a simple tissue. Hollander AP, Dickinson SC, Kafienah W, Stem Cells 2010, 28:1992-1996.

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REVIEW - Mesenchymal stem cells in arthritic diseases. Faye H Chen and Rocky S Tuan, Arthritis Research & Therapy 2008, 10:223

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Mesenchymal stem cells for cartilage repair in osteoarthritis. Pawan K Gupta1, Anjan K Das2, Anoop Chullikana1 and Anish S Majumdar. Stem Cell Research & Therapy 2012, 3:25 http://stemcellres.com/content/3/4/25

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Chondrogenesis and cartilage tissue engineering: the longer road to technology development. Mahmoudifar N1, Doran PM. Trends Biotechnol. 2012 Mar;30(3):166-76.

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Concise Review: The Clinical Application of Mesenchymal Stem Cells for Musculoskeletal Regeneration: Current Status and Perspectives

Andre F. Steinert, Lars Rackwitz, Fabian Gilbert, Ulrich Nöth and Rocky S. Tuan. Stem Cells Trans Med 2012, 1:237-247.

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Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. Caplan AI , J Cell Physiol 2007, 213:341-347.

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Different populations and sources of human mesenchymal stem cells (MSC): a comparison of adult and neonatal tissue-derived MSC. Hass R, Kasper C, Bohm S, Jacobs R - Cell Commun Signal 2011, 9:12

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Stem Cells and other innovative intra-articular therapies for osteoarthritis: What does the future hold? Singh A Jasvinder. BMC Medicine 2012, 10:44

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Marrow stromal cells as stem cells for nonhematopoietic tissues. Prockop DJ. Science. 1997 Apr 4;276(5309):71-4.

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Multilineage potential of adult human mesenchymal stem cells. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR . Science 1999,284:143-147.

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Stem cell therapy for cartilage regeneration in osteoarthritis. Koelling S1, Miosge N. Expert Opin Biol Ther. 2009 Nov;9(11):1399-405.

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Intraarticular treatments for osteoarthritis: new perspectives. Chevalier X. Curr Drug Targets. 2010 May;11(5):546-60.

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Mesenchymal stem cell-based HLA-independent cell therapy for tissue engineering of bone and cartilage. Niemeyer P1, Krause U, Kasten P, Kreuz PC, Henle P, Südkam NP, Mehlhorn A. Curr Stem Cell Res Ther. 2006 Jan;1(1):21-7.

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Repair of articular cartilage defects in the patello-femoral joint with autologous bone marrow mesenchymal cell transplantation: three case reports involving nine defects in five knees. Wakitani S1, Nawata M, Tensho K, Okabe T, Machida H, Ohgushi H. J Tissue Eng Regen Med. 2007 Jan-Feb;1(1):74-9.

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Autologous bone marrow-derived mesenchymal stem cells versus autologous chondrocyte implantation: an observational cohort study. Nejadnik H1, Hui JH, Feng Choong EP, Tai BC, Lee EH. Am J Sports Med. 2010 Jun;38(6):1110-6.

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Mesenchymal stem cell therapy for knee osteoarthritis. Preliminary report of four patients. Davatchi F1, Abdollahi BS, Mohyeddin M, Shahram F, Nikbin B. Int J Rheum Dis. 2011 May;14(2):211-5.

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Intra-articular injection of autologous mesenchymal stem cells in six patients with knee osteoarthritis. Emadedin M1, Aghdami N, Taghiyar L, Fazeli R, Moghadasali R, Jahangir S, Farjad R, Baghaban Eslaminejad M. Arch Iran Med. 2012 Jul;15(7):422-8.

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Autologous bone marrow mesenchymal stem cells implantation for cartilage defects: two cases report. Kasemkijwattana C1, Hongeng S, Kesprayura S, Rungsinaporn V, Chaipinyo K, Chansiri K. J Med Assoc Thai. 2011 Mar;94(3):395-400.

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Increased knee cartilage volume in degenerative joint disease using percutaneously implanted, autologous mesenchymal stem cells. Centeno CJ1, Busse D, Kisiday J, Keohan C, Freeman M, Karli D. Pain Physician. 2008 May-Jun;11(3):343-53.

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Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells. A pilot study. Gangji V1, Hauzeur JP, Matos C, De Maertelaer V, Toungouz M, Lambermont M. J Bone Joint Surg Am. 2004 Jun;86-A(6)

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Treatment of a full-thickness articular cartilage defect in the femoral condyle of an athlete with autologous bone-marrow stromal cells. Kuroda R1, Ishida K, Matsumoto T, Akisue T, Fujioka H, Mizuno K, Ohgushi H, Wakitani S, Kurosaka M., Osteoarthritis Cartilage. 2007 Feb;15(2):226-31.

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The Clinical Use of Human Culture-Expanded Autologous Bone Marrow Mesenchymal Stem Cells Transplanted on Platelet-Rich Fibrin Glue in the Treatment of Articular Cartilage Defects: A Pilot Study and Preliminary Results. Haleem AM1, Singergy AA, Sabry D, Atta HM, Rashed LA, Chu CR, El Shewy MT, Azzam A, Abdel Aziz MT. Cartilage. 2010 Oct;1(4):253-261.

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Bone marrow aspirate and bone allograft to treat acetabular bone defects in revision total hip arthroplasty: preliminary report. Vulcano E1, Murena L, Falvo DA, Baj A, Toniolo A, Cherubino P. Eur Rev Med Pharmacol Sci. 2013 Aug;17(16):2240-9.

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