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Ankle

"I would recommend stem cell injections for anyone who is having discomfort " – Marion

PROVIDING NON-SURGICAL ALTERNATIVE TO JOINT AND BACK  PROBLEMS

Experience Counts - Located in Jacksonville, Florida, we are the leader in Adult Stem Cell and Platelet-Rich Plasma (PRP) Procedures. We have performed these procedures for more than ten years with over 90 % results and ZERO side effects.

Top Stem Cell Center in the World: Unique Proven Clinical Protocols, over ten years of experience and hundreds of satisfied patients is why people from around the world come to us for their adult stem cell and Platelet-Rich Plasma Procedures. 

FIVE reasons you need to know before you decide. You will see why people around the world choose us over other Clinics.

Glaring Differences

SmartChoice®

Clinic

 

Other Leading Stem Cell Clinics (including Regenexx, Cell surgical Networks and others)

1. Gene and Cellular tests to evaluate your stem cell functions.

YES

NO

2. Use BOTH Bone Marrow and Fat Stem Cells, along with PRP.

YES

NO

3. Process Your Stem Cells with safety and use no dangerous chemicals like collagenase.

YES

NO

4. Use Dynamic Ultrasound Guided Injections for Precision and safety (and NOT use X-Rays that can damage your cells).

YES

NO

5. Improve body functions with proprietary Hormones and Supplements, so you get the best possible clinical outcome.

YES

NO

 

As an ankle pain and ankle arthritis surgery alternatives, SmartChoice® Joint Procedures may help alleviate the cause of pain with simple office injection procedure. Patients are encouraged to walk the same day, and most experience almost no down time after the procedure.

ANKLE OA

At SmartChoice® Stem Cell Institute, we are leading non-surgical specialist for chronic ankle pain and injuries from:

 

PLANTER FASCITIS

We play a key role in this cutting-edge stem cell medical field. While many types of stem cells are currently used in orthopedic healing, the most common are mesenchymal stem cells and hematopoietic stem cells to help regenerate tissue and rebuild cartilage, muscles, tendons and ligaments.

Because it is now possible to induce pluripotency in cells that have not come from embryos, the controversial use of embryonic stem cells has fallen on the way side and in the favor of the accessible cells found within the patient’s own body.

Patients coping with arthritis, sports injuries, tendon strains, sprained ligaments, muscle injuries and more, will be comforted to know that surgery is not the only option of treatment available to them. Faster healing as well as improved functionality both are possible with innovative, cutting- edge adult stem cell and PRP procedures.

MEDICAL LITERATURE - PRP AND STEM CELLS IN ANKLE AND FOOT INJURIES

1. Shetty VD, Dhillon M, Hegde C, Jagtap P, Shetty S. A study to compare the efficacy of corticosteroid therapy with platelet-rich plasma therapy in recalcitrant plantar fasciitis: A preliminary report. Foot Ankle Surg. 2014 Mar;20(1):10-3. Epub 2013 Aug 16.
  
2. Kim E, Lee JH. Autologous platelet-rich plasma versus dextrose prolotherapy for the treatment of chronic recalcitrant plantar fasciitis. PM R. 2013 Jul 19.
 
3. Martinelli N, Marinozzi A, Carnì S, Trovato U, Bianchi A, Denaro V. Platelet-rich plasma injections for chronic plantar fasciitis. Int Orthop. 2012 Dec 19.
 
 4. Ragab EM, Othman AM. Platelets rich plasma for treatment of chronic plantar fasciitis. Arch Orthop Trauma Surg. 2012 Aug;132(8):1065-70.
 
 5. Stem cells and cartilage development: complexities of a simple tissue. Hollander AP, Dickinson SC, Kafienah W, Stem Cells 2010, 28:1992-1996. 
  
6. Current clinical therapies for cartilage repair, their limitation and the role of stem cells. Dhinsa BS, Adesida AB. Curr Stem Cell Res Ther. 2012 Mar;7(2):143-8. 2.
 
7.     Mesenchymal stem cell-based treatment for cartilage defects in osteoarthritis. Qi Y, Feng G, Yan W.  Mol Biol Rep. 2012 May;39(5):5683-9.
 
8.     Developments in stem cells: implications for future joint replacements. Proc Maclaine SE, McNamara LE, Bennett AJ, Dalby MJ, Meek RM. Inst Mech Eng H. 2013 Mar;227(3):275-83.
 
9.     Current surgical options for articular cartilage repair. Peretti GM, Pozzi A, Ballis R, Deponti D, Pellacci F.   Acta Neurochir Suppl. 2011;108:213-9.
 
10.  Mesenchymal stem cell-based treatment for cartilage defects in osteoarthritis Qi Y, Feng G, Yan W.Mol Biol Rep. 2012 May;39(5):5683-9.
 
11.  Prospects of stem cell therapy in osteoarthritis. Roberts, Genever, McCaskie & De Bari; Regen. Med. (2011) 6(3), 351–366).
 
12.  Current clinical therapies for cartilage repair, their limitation and the role of stem cells. Dhinsa BS, Adesida AB. Curr Stem Cell Res Ther. 2012 Mar;7(2):143-8.
 
13.  Mesenchymal stem cell-based treatment for cartilage defects in osteoarthritis. Qi Y, Feng G, Yan W. Mol Biol Rep. 2012 May;39(5):5683-9.
 
14.  Growth factors in the treatment of early osteoarthritis. Civinini R, Nistri L, Martini C, Redl B, Ristori G, Innocenti M. Clin Cases Miner Bone Metab. 2013 Jan;10(1):26-9.
 
15.  Mesenchymal stem cells in joint disease and repair. Barry F, Murphy M. Nat Rev Rheumatol. 2013 Jul 23.
 
16. Autologous bone marrow concentrate: review and application of a novel intra-articular orthobiologic for cartilage disease.Sampson S1, Botto-van Bemden A, Aufiero D.  Phys Sportsmed. 2013 Sep;41(3):7-18.

17.  Regenerative injection therapy with whole bone marrow aspirate for degenerative joint disease: a case series.Hauser RA1, Orlofsky A.   Clin Med Insights Arthritis Musculoskelet Disord. 2013 Sep 4;6:65-72. 
 
18.  Safety of autologous bone marrow aspiration concentrate transplantation: initial experiences in 101 patients. Hendrich C1, Franz E, Waertel G, Krebs R, Jäger M.  Orthop Rev (Pavia). 2009 Oct 10;1(2):e32
 
19. Stem cells and cartilage development: complexities of a simple tissue. Hollander AP, Dickinson SC, Kafienah W, Stem Cells 2010, 28:1992-1996. 
  
20.  Cartilage tissue engineering: towards a biomaterial assisted mesenchymal stem cell therapy. Vinatier C, Bouffi C, Merceron C, Gordeladze J, Brondello JM, Jorgensen C, Weiss P, Guicheux J, Noel D.  Curr Stem Cell Res Ther 2009, 4:318-329.

21. REVIEW - Mesenchymal stem cells in arthritic diseases. Faye H Chen and Rocky S Tuan,  Arthritis Research & Therapy 2008, 10:223
 
22.  Mesenchymal stem cells for cartilage repair in osteoarthritis. Pawan K Gupta1, Anjan K Das2, Anoop Chullikana1 and Anish S Majumdar. Stem Cell Research & Therapy 2012, 3:25 http://stemcellres.com/content/3/4/25
 
23.  Stem Cell Prolotherapy in Regenerative Medicine -Background, Theory and Protocols,  Donna D. Alderman, DO, Robert W. Alexander, MD, DMD, FICS, Gerald R. Harris, DO, Patrick C. Astourian, MS, PA-C, JOURNAL of PROLOTHERAPY | VOLUME 3, ISSUE 3 | AUGUST 2011
 
24.  Chondrogenesis and cartilage tissue engineering: the longer road to technology development.  Mahmoudifar N1, Doran PM.  Trends Biotechnol. 2012 Mar;30(3):166-76.

25. Concise Review: The Clinical Application of Mesenchymal Stem Cells for Musculoskeletal Regeneration: Current Status and Perspectives. Andre F. Steinert, Lars Rackwitz, Fabian Gilbert, Ulrich Nöth and Rocky S. Tuan. Stem Cells Trans Med 2012, 1:237-247.

26.  Adult mesenchymal stem cells for tissue engineering versus regenerative medicine.  Caplan AI ,  J Cell Physiol 2007, 213:341-347.
 
27.  Different populations and sources of human mesenchymal stem cells (MSC): a comparison of adult and neonatal tissue-derived MSC. Hass R, Kasper C, Bohm S, Jacobs R  - Cell Commun Signal 2011, 9:12
 
28.  Stem Cells and other innovative intra-articular therapies for osteoarthritis: What does the futurehold? Singh A Jasvinder. BMC Medicine 2012, 10:44
 
29. Marrow stromal cells as stem cells for nonhematopoietic tissues.  Prockop DJ. Science. 1997 Apr 4;276(5309):71-4.
 
30.  Multilineage potential of adult human mesenchymal stem cells. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR . Science 1999,284:143-147.
 
31.   Stem cell therapy for cartilage regeneration in osteoarthritis.Koelling S1, Miosge N. Expert Opin Biol Ther. 2009 Nov;9(11):1399-405.

 32. Intraarticular treatments for osteoarthritis: new perspectives. Chevalier X.Curr Drug Targets. 2010 May;11(5):546-60.

33.  Mesenchymal stem cell-based HLA-independent cell therapy for tissue engineering of bone and cartilage. Niemeyer P1, Krause U, Kasten P, Kreuz PC, Henle P, Südkam NP, Mehlhorn A.  Curr Stem Cell Res Ther. 2006 Jan;1(1):21-7.

34.  Autologous bone marrow-derived mesenchymal stem cells versus autologous chondrocyte implantation: an observational cohort study. Nejadnik H1, Hui JH, Feng Choong EP, Tai BC, Lee EH.  Am J Sports Med. 2010 Jun;38(6):1110-6.

35.  Autologous bone marrow mesenchymal stem cells implantation for cartilage defects: two cases report. Kasemkijwattana C1, Hongeng S, Kesprayura S, Rungsinaporn V, Chaipinyo K, Chansiri K.   J Med Assoc Thai. 2011 Mar;94(3):395-400.
 
36.  The Clinical Use of Human Culture-Expanded Autologous Bone Marrow Mesenchymal Stem Cells Transplanted on Platelet-Rich Fibrin Glue in the Treatment of Articular Cartilage Defects: A Pilot Study and Preliminary Results. Haleem AM1, Singergy AA, Sabry D, Atta HM, Rashed LA, Chu CR, El Shewy MT, Azzam A, Abdel Aziz MT.   Cartilage. 2010 Oct;1(4):253-261

 

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