A Possible Minimally Invasive Alternative for Artificial Joint Replacement
A brand new therapy for the treatment of degenerations of joint, muscle and ligament is the Regenerative Medicine, focusing in particular on the transplantation of autologous adult stem cells.
Articular cartilage is a complex and highly complicated tissue and plays a key role in the buffering of heavy mechanical loads that strain articular joints. Lesions, trauma or injury to the cartilage can – in case of failure of the body’s own reparative capacity - lead to degenerative processes that can result in arthritis.
Attempts to stimulate the regeneration of cartilage by means of non-invasive methods can induce the production of fibrous cartilage, however not the regeneration of a fully functional, intact and resistant hyaline cartilage that can withstand general or athletic stresses.
Many patients experience a temporary palliation of their complaints, but further degeneration of their cartilage can hardly be averted, most likely resulting in artificial joint replacement.
Mesenchymal stem cells in joint disease and repair
Based on new medical findings and against this background, new therapy concepts emerge. Today, autologous adult stem cells are deployed for the therapy of damaged cartilage, articular capsule, ligament and musculature. Cartilage composes of chondrocytes that evolve from mesenchymal stem cells during the embryonic development. According to newest research, mesenchymal adult stem cells can be extracted from bone marrow. Further findings suggest that haemopoietic stem cells are able to differentiate into cartilage-, bone- and muscle-cells in clinical trials
In new research, scientists note that Mesenchymal stem cells are known to have a potential for articular cartilage regeneration. Now doctors have found that for the treatment of generalized cartilage loss in osteoarthritis that injection therapy is a good alternative to the surgery.
For those of us affected by osteoarthritis, we know too well the impact it has on the quality of life and daily living activities. Your own Stem cell injections for osteoarthritis can help maintain healthy tissues by acting as repair cells and by reducing inflammation. The injection of Mesenchymal stem cells has also produced promising outcomes in preclinical models of joint disease.
Research regarding stem cell injections for osteoarthritis
More and more research is now showing that stem cell therapies have encouraging results. They have also confirmed safety and strong indications of clinical efficacy were identified.
Patients exhibited rapid and progressive improvement. . . Researchers quote - “Stem Cell therapy may be a valid alternative treatment for chronic knee osteoarthritis. The intervention is simple, does not require hospitalization or surgery, provides pain relief, and significantly improves cartilage quality.”
Advancements in Treating Chronic Joint and Back Pain with your own Stem Cells
If you are suffering from crippling, degenerative joint disease – stem cell therapy may be the breakthrough treatment you are looking for.
We have been recognized as a leader in using cutting-edge, non-surgical options for degenerative joint disease, arthritis, tendonitis, and also for fast and complete repair of sports’ related injuries.
What is Stem Cell Therapy?
As practiced at SmartChoice Stem Cell Institute, Stem cells are derived from your own body. Stem Cells are extracted from bone marrow and fat. These stem cells help the body renew and heal itself and provide a special role in the non-surgical treatment of osteoarthritis, treatment of chronic pain, and sports injuries.
Our body possesses the power of repair by the stem cell, but it often will need to be concentrated in an area of injury or chronic degeneration to be truly effective. Symptoms associated with the following conditions can possibly be treated by Stem cell injections:
- Rotator cuff tendonitis
- Biceps tendonitis
- Osteochondral defects
- Labral tears of the hip and shoulder
- Chronic epicondylitis (tennis and golfer’s elbow)
- Ligament injuries
- Degenerative disc disease
- Chronic neck and back pain
- Chronic Headaches
- Chronic groin and hamstring strains
- Avascular necrosis of the hip
- Non-healing fractures
Stem cell therapy is performed by extracting stem cells from your own body, purifying them, and then injecting them back into the damaged area – all at the same setting. The stem cells cannot work alone, and they require help from growth and support factors found in Platelet-Rich Plasma.
We follow strict FDA guidelines in the use of your stem cells, and at no time do we manipulate, expand, or grow stem cells in culture or store your stem cells.
The area of injury or arthritis is treated with both stem cells (from Bone marrow and fat tissue) and platelet rich plasma (PRP). If stem cells are the seeds in the lawn, PRP is the fertilizer that helps the lawn grow. PRP, a combination of growth factors and cytokines naturally found in the body, provides cell nourishment to help these stem cells flourish and repair naturally.
Most cases of adult stem cell and PRP treatments are successful, and you can avoid the pain, disability, down time, and risk associated with major orthopedic surgery. There is minimal recovery from our treatments. There have been no reports of serious side effects in the scientific literature when adult mesenchymal stem cells are used as office procedures.
Afterwards, we encourage the patient to use the joint normally, and follow up treatments of PRP may be needed in 4 to 6 weeks intervals to continue to allow the stem cells to do their work. Also, having treatment with stem cells does not make a person ineligible for surgery.
Our treatment plan of joint injuries, arthritis and chronic pain is unique when compared to other practices. A holistic view of orthopaedic Medicine is followed in several ways, we also look at the other problems associated with your condition – like gait abnormalities, spine malalignment etc. Furthermore, the whole person is treated at our Center, where a full discussion of diet, exercise, and supplementation (of vitamins and hormones) is reviewed.
We have had the opportunity to treat anyone from professional athletes to patients who have suffered for decades with chronic pain, and invite you to schedule a consultation with us to see how we can help you.
1. Jo CH, Lee YG, Shin WH, et al. Intra-articular injection of mesenchymal stem cells for the treatment of osteoarthritis of the knee: A proof-of-concept clinical trial. Stem Cells. 2014 Jan 21.
2. Barry F, Murphy M. Mesenchymal stem cells in joint disease and repair. Nat Rev Rheumatol. 2013 Jul 23.
3. Orozco L, Munar A, Soler R, et al. Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells: A Pilot Study. Transplantation. 2013 Jun 27;95 (12):1535-1541.
4. Caplan A.I., Bruder S.P. Mesenchymal Stem Cells: Building blogs for molecular medicine in the 21st century. Trends Mol Med, 7:259-264, 2001.
5. Caplan A.I. Mesenchymal Stem Cells. J Ortop Res 9:641-650, 1991.
6. Deans, R.J., Moseley A.B. Mesenchymal Stem Cells: Biology and potential clinical uses. Exp Hematol, 28:875-884, 2000.